RORC Polyclonal antibody

RORC Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 29910-1-AP

Print datasheet

Synonyms

RORG, ROR gamma T, Retinoid-related orphan receptor-gamma, RAR-related orphan receptor C, Nuclear receptor ROR-gamma



经过测试的应用

Positive WB detected inmouse colon tissue, mouse liver tissue, mouse testis tissue, rat liver tissue, rat testis tissue, rat thymus tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

29910-1-AP targets RORC in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Immunogen RORC fusion protein Ag31783 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name RAR-related orphan receptor C
Synonyms RORG, ROR gamma T, Retinoid-related orphan receptor-gamma, RAR-related orphan receptor C, Nuclear receptor ROR-gamma
Calculated Molecular Weight 518 aa, 58 kDa
Observed Molecular Weight56 kDa
GenBank Accession NumberBC031554
Gene Symbol RORC
Gene ID (NCBI) 6097
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP51449
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The Nuclear receptors retinoic acid receptor-related orphan receptor gamma (RORγ or RORc, also known as NR1F3) was the third and most recent ROR group member to be discovered, following the prior disclosures of RORα (RORa or NR1F1) and RORβ (RORb or NR1F2) (PMID:24502334). Studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.RORC has 2 isoforms with the MW of 56 kDa and 58 kDa.

实验方案

Product Specific Protocols
WB protocol for RORC antibody 29910-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Int Immunopharmacol

SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sjögren's syndrome

Authors - Peini Hu