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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
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0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of mouse eye using 16891-1-AP (same clone as 16891-1-PBS)

    WB analysis of mouse eye using 16891-1-AP (same clone as 16891-1-PBS)

    mouse eye tissue were subjected to SDS PAGE followed by western blot with 16891-1-AP (RPGR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16891-1-PBS in a different storage buffer formulation.

  • IF Staining of hTERT-RPE1 cells using 16891-1-AP (same clone as 16891-1-PBS)

    IF Staining of hTERT-RPE1 cells using 16891-1-AP (same clone as 16891-1-PBS)

    IF result of anti-RPGR (16891-1-AP) in hTERT-RPE1 cell by Dr. Seongjin Seo. This data was developed using the same antibody clone with 16891-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse eye using 16891-1-AP (same clone as 16891-1-PBS)

    IHC staining of mouse eye using 16891-1-AP (same clone as 16891-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 16891-1-AP (RPGR antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16891-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse eye using 16891-1-AP (same clone as 16891-1-PBS)

    IHC staining of mouse eye using 16891-1-AP (same clone as 16891-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 16891-1-AP (RPGR antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16891-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 16891-1-AP (same clone as 16891-1-PBS)

    IHC staining of human kidney using 16891-1-AP (same clone as 16891-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 16891-1-AP (RPGR Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 16891-1-PBS in a different storage buffer formulation.

RPGR Polyclonal antibody, PBS Only

RPGR Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 16891-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

16891-1-PBS targets RPGR in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 RPGR fusion protein Ag10405 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 retinitis pigmentosa GTPase regulator
别名
计算分子量 113 kDa
观测分子量 100-105 kDa, 70 kDa
GenBank蛋白编号BC031624
基因名称 RPGR
Gene ID (NCBI) 6103
RRIDAB_2181130
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ92834
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RPGR is a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. This antibody can recognize all the isoforms of RPGR.