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  • KD/KO Validated

RSPO2 Polyclonal antibody

RSPO2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, ELISA and More (2)

Conjugate

Unconjugated

Cat no : 17781-1-AP

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Synonyms

CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2



产品信息

17781-1-AP targets RSPO2 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB, IF, IHC
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, pig
Immunogen RSPO2 fusion protein Ag11216 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name R-spondin 2 homolog (Xenopus laevis)
Synonyms CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2
Calculated Molecular Weight 243 aa, 28 kDa
Observed Molecular Weight 33 kDa
GenBank Accession NumberBC027938
Gene Symbol RSPO2
Gene ID (NCBI) 340419
RRIDAB_2269700
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6UXX9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

RSPO2 is one of the R-spondins (RSPOs) which comprise a family of four secreted proteins that have important roles in cell proliferation, cell fate determination and organogenesis. RSPOs typically exert their effects by potentiating the Wnt/beta-catenin signaling pathway. Overexpression of Rspo2 is sufficient to promote bone morphogenetic protein-induced mineralization Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse mammary tumors.

发表文章

SpeciesApplicationTitle
human,mouseWB,IF

Cardiovasc Res

Role of R-spondin 2 in arterial lymphangiogenesis and atherosclerosis.

Authors - Bhupesh Singla
mouseWB,IF

Int J Mol Sci

R-Spondin2, a Positive Canonical WNT Signaling Regulator, Controls the Expansion and Differentiation of Distal Lung Epithelial Stem/Progenitor Cells in Mice.

Authors - Ahmed A Raslan
humanWB,IHC

J Cancer

miR-497-5p-RSPO2 axis inhibits cell growth and metastasis in glioblastoma.

Authors - Kun Chen
humanWB

DNA Cell Biol

Expression and Prognostic Values of the Roof Plate-Specific Spondin Family in Bladder Cancer.

Authors - Lei Gao
humanWB

Mol Biol Rep

RSPO fusion transcripts in colorectal cancer in Japanese population.

Authors - Kazuya Shinmura
mouseIF

BMC Res Notes

R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability.

Authors - S R Jackson
  • KO Validated