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  • Featured Product
  • KD/KO Validated

RTN2 Polyclonal antibody, PBS Only

RTN2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11168-1-PBS

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Synonyms

验证数据展示

  • WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

  • IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 11168-1-AP (RTN2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

  • IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 11168-1-AP (RTN2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

产品信息

11168-1-PBS targets RTN2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen RTN2 fusion protein Ag1655 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name reticulon 2
Synonyms
Calculated Molecular Weight 59 kDa, 51 kDa, 22 kDa
Observed Molecular Weight 20-23 kDa
GenBank Accession NumberBC014244
Gene Symbol RTN2
Gene ID (NCBI) 6253
RRIDAB_10644321
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO75298
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Reticulon (RTN) proteins are a group of membrane-bound proteins that largely reside in endoplasmic reticulum (ER) (PMID: 18177508). Reticulon proteins share a common sequence feature, the reticulon homology domain (RHD). They are involved in shaping the tubular endoplasmic reticulum network, membrane trafficking, inhibition of axonal growth, and apoptosis (PMID: 24218324). Four mammalian reticulons (RTN1-4) exist. Human RTN2 gene produces three isoforms termed RTN2-A, RTN2-B, and RTN2-C. Isoform RTN2-C has a calculated molecular weight of 22 kDa and is highly expressed in skeletal muscle.