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Recombinant Rat Adiponectin protein (His Tag)

种属

Rat

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0872

Print datasheet

Synonyms

Adipoq, Acdc, Acrp30, Adiponectin

验证数据展示

  • Purity of Recombinant Rat Adiponectin was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Rat Adiponectin was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 CHO-derived Rat Adiponectin protein Ile19-Asn244 (Accession# Q8K3R4) with a His tag at the C-terminus.
基因ID 246253
蛋白编号 Q8K3R4
预测分子量 25.2 kDa
SDS-PAGE 25-29 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Adiponectin, also known as Acrp30, AdipoQ, and GBP28, is an adipocyte-secreted protein that circulates in high concentrations in the serum and acts to increase insulin sensitivity. Adiponectin modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. The serum concentration of adiponectin decreases in obese patients, opposite to other adipocytokines. In recent studies, serum adiponectin level progressively decreased in patients according to the severity of obesity, insulin resistance, diabetes mellitus and cardiovascular diseases. Low serum adiponectin level may be a predictive factor for type 2 diabetes mellitus (T2DM) and other cardiovascular diseases.

参考文献:

1. Wang ZV, et al. (2016) J Mol Cell Biol. 8(2):93-100.
2. Liu M, et al. (2014) Best Pract Res Clin Endocrinol Metab.28(1):25-31.
3. Díez JJ, et al. (2003) Eur J Endocrinol.148(3):293-300.
4. Yamauchi T, et al. (2003) Nature.423(6941):762-9.