S1PR5/EDG8 Polyclonal antibody

S1PR5/EDG8 Polyclonal Antibody for WB, ELISA
Cat No. 13874-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, ELISA

Edg 8, EDG8, S1P receptor 5, S1P receptor Edg 8, S1P5, S1PR5, S1PR5/EDG8, SPPR 1, SPPR 2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse brain tissue, HEK-293 cells, HeLa cells, Jurkat cells, K-562 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 2 publications below

产品信息

13874-1-AP targets S1PR5/EDG8 in WB, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB
经测试反应性 human, mouse
文献引用反应性human, mouse
免疫原 S1PR5/EDG8 fusion protein Ag4928 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sphingosine-1-phosphate receptor 5
别名 Edg 8, EDG8, S1P receptor 5, S1P receptor Edg 8, S1P5, S1PR5, S1PR5/EDG8, SPPR 1, SPPR 2
计算分子量 398 aa, 42 kDa
观测分子量 50-55 kDa
GenBank蛋白编号BC034703
基因名称 S1PR5
Gene ID (NCBI) 53637
RRIDAB_2182638
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H228
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Sphingosine 1-phosphate (S1P) is a biologically active lysophospholipid that elicits diverse physiological effects on most types of cells and tissues via five G protein-coupled receptors, S1PR1 to S1PR5. S1PRs differ in their tissue expression and cell lineage: S1PR1-3 are expressed throughout the immune, central nervous system (CNS), and cardiovascular system; S1PR4 is primarily expressed in lymphoid tissue; and S1PR5 is a predominant receptor in CNS white matter, spleen and natural killer cells (PMID: 21707490). S1PR5 (also known as EDG8) has been involved in the trafficking of NK cells and monocytes (PMID: 21911833; 23519784).

实验方案

Product Specific Protocols
WB protocol for S1PR5/EDG8 antibody 13874-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

PLoS One

Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2.

Authors - Rie Matsushima-Nishiwaki
mouseWB

Drug Des Devel Ther

Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence.

Authors - Dianna Liu
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