验证数据展示
经过测试的应用
Positive IHC detected in | human liver cancer tissue, human liver tissue, human small intestine tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
应用 | 推荐稀释比 |
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Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
KD/KO | See 1 publications below |
WB | See 1 publications below |
IHC | See 2 publications below |
产品信息
16721-1-AP targets SAA in WB, IHC, ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, ELISA Application Description |
文献引用应用 | WB, IHC |
经测试反应性 | human |
文献引用反应性 | human |
免疫原 | SAA fusion protein Ag10160 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | serum amyloid A1 |
别名 | SAA1, serum amyloid A1, Serum amyloid A-1 protein, Serum amyloid protein A(2-102), Serum amyloid protein A(2-103) |
计算分子量 | 122 aa, 14 kDa |
GenBank蛋白编号 | BC105796 |
基因名称 | SAA1 |
Gene ID (NCBI) | 6288 |
RRID | AB_3085507 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P0DJI8 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Serum amyloid A1(SAA1) is a member of the serum amyloid A family of apolipoproteins. SAA1 is an acute phase apolipoprotein reactant produced mainly by hepatocytes and under regulation of inflammatory cytokines. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. Elevated serum SAA1 protein levels may be associated with lung cancer(PMID: 1463770). This antibody can recognize SAA1 and SAA2.
实验方案
Product Specific Protocols | |
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IHC protocol for SAA antibody 16721-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
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Mol Oncol Serum amyloid A1 in combination with integrin αVβ3 increases glioblastoma cells mobility and progression.
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J Transl Med Plasma proteomic analysis of autoimmune hepatitis in an improved AIH mouse model. |