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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 16246-1-AP (same clone as 16246-1-PBS)

    WB analysis using 16246-1-AP (same clone as 16246-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16246-1-AP (SAT2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16246-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 16246-1-AP (same clone as 16246-1-PBS)

    IHC staining of human cervical cancer using 16246-1-AP (same clone as 16246-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 16246-1-AP (SAT2 antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16246-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 16246-1-AP (same clone as 16246-1-PBS)

    IHC staining of human cervical cancer using 16246-1-AP (same clone as 16246-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 16246-1-AP (SAT2 antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16246-1-PBS in a different storage buffer formulation.

SAT2 Polyclonal antibody, PBS Only

SAT2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 16246-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

16246-1-PBS targets SAT2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 SAT2 fusion protein Ag9179 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 spermidine/spermine N1-acetyltransferase family member 2
别名
计算分子量 170 aa, 19 kDa
观测分子量 19 kDa
GenBank蛋白编号BC011751
基因名称 SAT2
Gene ID (NCBI) 112483
RRIDAB_2254874
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96F10
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Spermidine/spermine N1-acetyltransferase 2 (SAT2) is a short-lived polyamine catabolic enzyme inducible by polyamines and polyamine analogues. Human SAT2 contains the highly conserved acetyl-CoA-binding domain and displays coactivator function to enhance NF-κB-dependent transcription and enhances TNFα-induced NF-κB activity (PMID: 17875644). Human SAT1 and SAT2 proteins, which share 46% amino acid sequence identity and are clearly homologous, both interact with HIF-1α and both promote the ubiquitination and degradation of HIF-1α (PMID: 17011643).