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SAT2 Polyclonal antibody, PBS Only

SAT2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 16246-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 16246-1-AP (same clone as 16246-1-PBS)

    WB analysis using 16246-1-AP (same clone as 16246-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16246-1-AP (SAT2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16246-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 16246-1-AP (same clone as 16246-1-PBS)

    IHC staining of human cervical cancer using 16246-1-AP (same clone as 16246-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 16246-1-AP (SAT2 antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16246-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 16246-1-AP (same clone as 16246-1-PBS)

    IHC staining of human cervical cancer using 16246-1-AP (same clone as 16246-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 16246-1-AP (SAT2 antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16246-1-PBS in a different storage buffer formulation.

产品信息

16246-1-PBS targets SAT2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SAT2 fusion protein Ag9179 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name spermidine/spermine N1-acetyltransferase family member 2
Synonyms
Calculated Molecular Weight 170 aa, 19 kDa
Observed Molecular Weight 19 kDa
GenBank Accession NumberBC011751
Gene Symbol SAT2
Gene ID (NCBI) 112483
RRIDAB_2254874
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96F10
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Spermidine/spermine N1-acetyltransferase 2 (SAT2) is a short-lived polyamine catabolic enzyme inducible by polyamines and polyamine analogues. Human SAT2 contains the highly conserved acetyl-CoA-binding domain and displays coactivator function to enhance NF-κB-dependent transcription and enhances TNFα-induced NF-κB activity (PMID: 17875644). Human SAT1 and SAT2 proteins, which share 46% amino acid sequence identity and are clearly homologous, both interact with HIF-1α and both promote the ubiquitination and degradation of HIF-1α (PMID: 17011643).