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SBE-β-CD

SBE-β-CD (Sulfobutylether-β-Cyclodextrin) 是一种磺基丁基醚 β-环糊精衍生物，其磺酸钠盐通过丁基醚间隔基团或磺基丁基醚与亲脂腔隔开。

CAS号

182410-00-0

分子式

主要靶点

Others

仅限科研使用

Cat No : CM01559

Print datasheet

Synonyms

Sulfobutylether-β-Cyclodextrin|磺丁基-Β-环糊精

验证数据展示

  • CAS No.: 182410-00-0

    SBE-β-CD
    CAS#: 182410-00-0

产品信息

SBE-β-CD is a sulfobutylether β-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether (SBE).

CAS号 182410-00-0
分子式
主要靶点 Others
主要通路 其他
分子量
纯度 ， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Sulfobutylether-β-Cyclodextrin|磺丁基-Β-环糊精

溶解度

DMSO:5.625 mg/mL,Sonification/heating is recommended.,H2O:250 mg/mL,Sonification is recommended.

参考文献

1.Fukuda M, et al.Influence of sulfobutyl ether beta-cyclodextrin (Captisol) on the dissolution properties of a poorly soluble drug from extrudates prepared by hot-melt extrusion.Int J Pharm. 2008 Feb 28;350(1-2):188-196
2.Lockwood SF, et al. Improved aqueous solubility of crystalline astaxanthin (3,3'-dihydroxy-beta, beta-carotene-4,4'-dione) by Captisol (sulfobutyl ether beta-cyclodextrin). J Pharm Sci. 2003 Apr;92(4):922-926.
3.Charman SA, et al. Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin. J Pharm Sci. 2006 Feb;95(2):256-67
4.Fettiplace MR, et al. Cardiac depression induced by cocaine or cocaethylene is alleviated by lipid emulsion more effectively than by sulfobutylether-β-cyclodextrin. Acad Emerg Med. 2015 May;22(5):508-17

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2