SCARA5 Polyclonal antibody
SCARA5 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | mouse liver tissue |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 1 publications below |
产品信息
55390-1-AP targets SCARA5 in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | WB, ELISA Application Description |
| Cited Applications | WB |
| Tested Reactivity | human, mouse |
| Cited Reactivity | mouse |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | scavenger receptor class A, member 5 (putative) |
| Synonyms | NET33, SCARA5, Scavenger receptor hlg, Tesr |
| Calculated Molecular Weight | 54 kDa |
| Observed Molecular Weight | 43 kDa |
| GenBank Accession Number | NM_173833 |
| Gene Symbol | SCARA5 |
| Gene ID (NCBI) | 286133 |
| RRID | AB_11182487 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6ZMJ2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SCARA5 belongs to the SCARA5 family. It is a ferritin receptor that mediates non-transferrin-dependent delivery of iron. SCARA5 mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. SCARA5 binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). This antibody can recognize isoform 1,2 and 3 of SCARA5.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SCARA5 antibody 55390-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Biomater Appl Prussian blue-modified ferritin nanoparticles for effective tumor chemo-photothermal combination therapy via enhancing reactive oxygen species production. |