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SCARF1 Polyclonal antibody

SCARF1 Polyclonal Antibody for WB, ELISA
Cat No. 13702-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse and More (1)

应用

WB, ELISA and More (2)

Acetyl LDL receptor, KIAA0149, SCARF1, SREC, SREC-I

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse lung tissue, unboiled mouse lung tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13702-1-AP targets SCARF1 in WB, IF, FC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB, IF, FC
经测试反应性 human, mouse
文献引用反应性human, mouse, rat
免疫原 SCARF1 fusion protein Ag4621 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 scavenger receptor class F, member 1
别名 Acetyl LDL receptor, KIAA0149, SCARF1, SREC, SREC-I
计算分子量 830 aa, 87 kDa
观测分子量 87 kDa
GenBank蛋白编号BC039735
基因名称 SCARF1
Gene ID (NCBI) 8578
RRIDAB_2182983
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ14162
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Scavenger receptor class F member 1 (SCARF1), also known as scavenger receptor expressed by endothelial cells (SREC)-I, belongs to the scavenger receptor (SR) superfamily. SCARF1 has been shown to bind modified low density lipoproteins (LDLs), including acetylated (Ac-) and oxidized (ox-) LDLs (PMID: 29725698; PMID: 15145948). In addition to binding and internalizing a diverse range of endogenous proteins, SCARF1 also binds a wide array of viral, fungal, and bacterial antigens (PMID: 29242513). SCARF1 has a calculated molecular weight of 87 kDa, with a molecular weight of 140-160 kDa due to N-glycosylation (PMID: 22279061; PMID: 15145948). SCARF1 can also exist as a dimer (~ 180 kDa) and a truncated soluble form (~ 60 kDa) (PMID: 29242513; PMID: 29725698).

实验方案

Product Specific Protocols
WB protocol for SCARF1 antibody 13702-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF

Nat Immunol

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.

Authors - Ramirez-Ortiz Zaida G ZG
  • KO Validated
ratWB

Cell Prolif

SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.

Authors - Xue-Song Xu
humanFC

Front Immunol

Neutrophil heterogeneity in complement C1q expression associated with sepsis mortality

Authors - Alissa Trzeciak
mouse

Cell Rep

Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development.

Authors - Tamihiro Kamata
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