SDCCAG1 Monoclonal antibody, PBS Only
SDCCAG1 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3C8A1
验证数据展示
产品信息
68708-1-PBS targets SDCCAG1 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | SDCCAG1 fusion protein Ag2467 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | serologically defined colon cancer antigen 1 |
Synonyms | Ribosome quality control complex subunit NEMF, NY CO 1, Nuclear export mediator factor, NEMF, Homo sapiens (Human) |
Calculated Molecular Weight | 1076 aa, 123 kDa |
Observed Molecular Weight | 130-140 kDa |
GenBank Accession Number | BC020794 |
Gene Symbol | SDCCAG1 |
Gene ID (NCBI) | 9147 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | O60524 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SDCCAG1, also named as NEMF, is a nuclear export mediator. It can be bound to translocon-engaged 60S subunits on native ER membranes. Human SDCCAG1 has been implicated in lung cancers and it may function as a tumor suppressor gene. SDCCAG1 inactivation contributes to the transformed state of human lung cancer cells (PMID:16103875, 10575219). NEMF is also regarded as a potential biomarker for the detection of active and latent TB infections (PMID: 26818387).