验证数据展示
产品信息
15512-1-AP targets SEC61alpha in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA Application Description |
| Tested Reactivity | human, mouse, rat |
| Immunogen | SEC61alpha fusion protein Ag7693 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | Sec61 alpha 1 subunit (S. cerevisiae) |
| Synonyms | |
| Calculated Molecular Weight | 52 kDa |
| GenBank Accession Number | BC002951 |
| Gene Symbol | SEC61alpha |
| Gene ID (NCBI) | 29927 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P61619 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The SEC61 complex is a major component of the endoplasmic reticulum (ER) translocation site (PMID: 7720858). This complex is composed of three subunits: SEC61alpha, SEC61beta and SEC61gamma. SEC61alpha is a polytopic integral membrane protein. It is a core component of the ER translocation complex, playing a crucial role in the insertion of secretory and membrane polypeptides into the ER (PMID: 9512475).
