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SERP1 Polyclonal antibody, PBS Only

SERP1 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17807-1-PBS

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Synonyms

验证数据展示

  • IP experiment of mouse brain using 17807-1-AP (same clone as 17807-1-PBS)

    IP experiment of mouse brain using 17807-1-AP (same clone as 17807-1-PBS)

    IP result of anti-SERP1 (IP:17807-1-AP, 4ug; Detection:17807-1-AP 1:500) with mouse brain tissue lysate 3160 ug. This data was developed using the same antibody clone with 17807-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse brain using 17807-1-AP (same clone as 17807-1-PBS)

    WB analysis of mouse brain using 17807-1-AP (same clone as 17807-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 17807-1-AP (SERP1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17807-1-PBS in a different storage buffer formulation.

  • IHC staining of human endometrial cancer using 17807-1-AP (same clone as 17807-1-PBS)

    IHC staining of human endometrial cancer using 17807-1-AP (same clone as 17807-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human endometrial cancer using 17807-1-AP (SERP1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17807-1-PBS in a different storage buffer formulation.

  • IHC staining of human endometrial cancer using 17807-1-AP (same clone as 17807-1-PBS)

    IHC staining of human endometrial cancer using 17807-1-AP (same clone as 17807-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human endometrial cancer using 17807-1-AP (SERP1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17807-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 17807-1-AP (same clone as 17807-1-PBS)

    IF Staining of HeLa using 17807-1-AP (same clone as 17807-1-PBS)

    Immunofluorescent analysis of (-20℃ Ethanol) fixed HeLa cells using 17807-1-AP (SERP1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 17807-1-PBS in a different storage buffer formulation.

产品信息

17807-1-PBS targets SERP1 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SERP1 fusion protein Ag12087 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name stress-associated endoplasmic reticulum protein 1
Synonyms
Calculated Molecular Weight 66 aa, 7 kDa
Observed Molecular Weight 10 kDa
GenBank Accession NumberBC108314
Gene Symbol SERP1
Gene ID (NCBI) 27230
RRIDAB_10597394
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y6X1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Stress-associated endoplasmic reticulum (ER) protein 1 (SERP1), also known as ribosome- associated membrane protein 4 (RAMP4), is a Sec61-associated polypeptide that is induced by ER stress [PMID:16705175]. SERP1 interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. It controls glycosylation of major histocompatibility complex class II-associated invariant chains by a translocational pausing mechanism, and its overexpression stabilizes newly synthesized membrane proteins under ER stress by associating with the Sec61 complex [PMID:10601334]. It is suggested SERP1 is involved in the biosynthesis/processing of secretory proteins