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SERPINB9 Monoclonal antibody, PBS Only

SERPINB9 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2H9D2

Cat no : 67950-1-PBS

Print datasheet

Synonyms

CAP 3, CAP3, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI 9, PI9, Serpin B9, SERPINB9

验证数据展示

  • WB analysis of K-562 using 67950-1-Ig (same clone as 67950-1-PBS)

    WB analysis of K-562 using 67950-1-Ig (same clone as 67950-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67950-1-Ig (SERPINB9 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67950-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse lung using 67950-1-Ig (same clone as 67950-1-PBS)

    IHC staining of mouse lung using 67950-1-Ig (same clone as 67950-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 67950-1-Ig (SERPINB9 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67950-1-PBS in a different storage buffer formulation.

  • IF Staining of C6 using 67950-1-Ig (same clone as 67950-1-PBS)

    IF Staining of C6 using 67950-1-Ig (same clone as 67950-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed C6 cells using SERPINB9 antibody (67950-1-Ig, Clone: 2H9D2 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67950-1-PBS in a different storage buffer formulation.

产品信息

67950-1-PBS targets SERPINB9 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity Human, Mouse, Rat
Immunogen SERPINB9 fusion protein Ag6719 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name serpin peptidase inhibitor, clade B (ovalbumin), member 9
Synonyms CAP 3, CAP3, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI 9, PI9, Serpin B9, SERPINB9
Calculated Molecular Weight 42 kDa
Observed Molecular Weight38 kDa
GenBank Accession NumberBC002538
Gene Symbol SERPINB9
Gene ID (NCBI) 5272
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP50453
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SERPINB9, also named as PI-9, belongs to the serpin family. SERPINB9 is an intracellular inhibitor of granzyme B (grB) that protects cytotoxic lymphocytes from grB-mediated death. It has a nucleo-cytoplasmic distribution and is produced in CD8+ T cells and natural killer cells (PMID: 28024184). Also, SERPINB9 is expressed by vascular SMCs and endothelial cells to avoid GZB-induced apoptosis (PMID: 28743062). The molecular weight of SERPINB9 is 42 kDa.