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SERTAD1 Polyclonal antibody

SERTAD1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 10167-1-AP

Print datasheet

Synonyms

CDK4 binding protein p34SEI1, SEI 1, SEI1, SERTA domain containing 1, SERTAD1, TRIP Br1

验证数据展示

  • IHC staining of mouse heart using 10167-1-AP

    IHC staining of mouse heart using 10167-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 10167-1-AP (SERTAD1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of mouse heart using 10167-1-AP

    IHC staining of mouse heart using 10167-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 10167-1-AP (SERTAD1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

经过测试的应用

Positive IHC detected inmouse heart tissue, mouse embryo tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10167-1-AP targets SERTAD1 in IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human, mouse
Immunogen SERTAD1 fusion protein Ag0180 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name SERTA domain containing 1
Synonyms CDK4 binding protein p34SEI1, SEI 1, SEI1, SERTA domain containing 1, SERTAD1, TRIP Br1
Calculated Molecular Weight 25 kDa
Observed Molecular Weight 25 kDa
GenBank Accession NumberBC002670
Gene Symbol SERTAD1
Gene ID (NCBI) 29950
RRIDAB_2285697
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UHV2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SERTA domain containing 1 (SERTAD1, synonyms: SEI1, TRIP-Br1) protein is a cyclin-dependent kinase 4 (cdk4)-binding protein and acts as a growth factor sensor and facilitates the formation and activation of cyclin D-CDK complexes in the face of inhibitory levels of INK4 proteins, therefore, antagonizes the activity of p16(INK4a) tumor suppressor. SERTAD1 also suppresses CREB-mediated transcription and regulates cell cycle progression through sequential effects on the transcriptional activity of E2F-responsive promoters during G(1) and S phases.

实验方案

Product Specific Protocols
IHC protocol for SERTAD1 antibody 10167-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols