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  • Featured Product
  • KD/KO Validated

SETD7 Polyclonal antibody, PBS Only

SETD7 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 24840-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 24840-1-AP (same clone as 24840-1-PBS)

    WB analysis using 24840-1-AP (same clone as 24840-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 24840-1-AP (SETD7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24840-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 24840-1-AP (same clone as 24840-1-PBS)

    IF Staining of HeLa using 24840-1-AP (same clone as 24840-1-PBS)

    Immunofluorescent analysis of (10% Formaldehyde) fixed HeLa cells using 24840-1-AP (SETD7 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24840-1-PBS in a different storage buffer formulation.

产品信息

24840-1-PBS targets SETD7 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SETD7 fusion protein Ag18219 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name SET domain containing (lysine methyltransferase) 7
Synonyms
Calculated Molecular Weight 366 aa, 41 kDa
Observed Molecular Weight 48-50 kDa
GenBank Accession NumberBC121055
Gene Symbol SETD7
Gene ID (NCBI) 80854
RRIDAB_2737406
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8WTS6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SET domain containing lysine methyltransferase 7 (SETD7, also called SET7/9) was the first lysine methyltransferase (KMT) discovered to specifically monomethylate lysine-4 of histone 3 (H3K4me1) (PMID: 26435321). SETD7 has been shown to have a very broad target specificity in vitro, including transcriptional regulators such as TAF10, p53, ER, p65, STAT3, Rb, Mypt, Tat, and Foxo3 (PMID: 25136132, 30013796).