验证数据展示
产品信息
11635-1-PBS targets SF1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | SF1 fusion protein Ag2209 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | splicing factor 1 |
Synonyms | |
Calculated Molecular Weight | 638 aa, 68 kDa |
Observed Molecular Weight | 65-71 kDa |
GenBank Accession Number | BC020217 |
Gene Symbol | SF1 |
Gene ID (NCBI) | 7536 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q15637 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SF1 is a nuclear pre-mRNA splicing factor, it specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The molecular weight of SF1 ranges from 59 kDa to 71 kDa due to alternative splicing.