验证数据展示
产品信息
15328-1-PBS targets SFRP4 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, rat samples.
Tested Applications | WB, IHC, IP, Indirect ELISA Application Description |
Tested Reactivity | human, rat |
Immunogen | SFRP4 fusion protein Ag6909 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | secreted frizzled-related protein 4 |
Synonyms | |
Calculated Molecular Weight | 40 kDa |
Observed Molecular Weight | 41-51 kDa, 55 kDa |
GenBank Accession Number | BC058911 |
Gene Symbol | SFRP4 |
Gene ID (NCBI) | 6424 |
RRID | AB_2187099 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q6FHJ7 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRP4 functions as a suppressor of tumor growth via inhibition of the Wnt signaling pathway.Downregulation or deletion of SFRP4 has been reported in several cancers and cell lines such as endometrial cancer, ovarian cancer, lung cancer,and others. This antibody got 41-51 kDa and 55 kDa bands in western blotting maybe due to differential posttranslational protein modification.