• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

SGLT2 Polyclonal antibody, PBS Only

SGLT2 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28683-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 28683-1-AP (same clone as 28683-1-PBS)

    WB analysis using 28683-1-AP (same clone as 28683-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28683-1-AP (SGLT2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28683-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 28683-1-AP (same clone as 28683-1-PBS)

    IHC staining of human kidney using 28683-1-AP (same clone as 28683-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 28683-1-AP (SGLT2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28683-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 28683-1-AP (same clone as 28683-1-PBS)

    IF Staining of mouse kidney using 28683-1-AP (same clone as 28683-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse kidney tissue using SGLT2 antibody (28683-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 28683-1-PBS in a different storage buffer formulation.

  • IF Staining of rat kidney using 28683-1-AP (same clone as 28683-1-PBS)

    IF Staining of rat kidney using 28683-1-AP (same clone as 28683-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed rat kidney tissue using SGLT2 antibody (28683-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 28683-1-PBS in a different storage buffer formulation.

产品信息

28683-1-PBS targets SGLT2 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SGLT2 fusion protein Ag30120 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier family 5 (sodium/glucose cotransporter), member 2
Synonyms
Calculated Molecular Weight 672 aa, 73 kDa
Observed Molecular Weight73 kDa
GenBank Accession NumberBC131542
Gene Symbol SGLT2
Gene ID (NCBI) 6524
RRIDAB_2918190
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP31639
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Sodium-glucose cotransporter 2 (SGLT2), encoded by SLC5A2, utilizes the electrochemical sodium gradient to transport glucose against the cell's internal concentration gradient. Mainly expressed on brush border membrane (BBM) of epithelial cells in the early segment of the proximal tubule, SGLT2 mediates most of the glucose reabsorption by the kidney overall. Inhibition of SGLT2 could improve glucose homeostasis of diabetic patients, which has been considered as a novel strategy for diabetes treatment.