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Conjugate
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Conjugate
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Conjugate
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SH2D1A Polyclonal antibody, PBS Only

SH2D1A Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11868-1-PBS

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Synonyms

验证数据展示

  • WB analysis of mouse thymus using 11868-1-AP (same clone as 11868-1-PBS)

    WB analysis of mouse thymus using 11868-1-AP (same clone as 11868-1-PBS)

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with 11868-1-AP (SH2D1A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11868-1-PBS in a different storage buffer formulation.

产品信息

11868-1-PBS targets SH2D1A in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SH2D1A fusion protein Ag2450 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name SH2 domain protein 1A
Synonyms
Calculated Molecular Weight 128 aa, 14 kDa
Observed Molecular Weight 16 kDa
GenBank Accession NumberBC020732
Gene Symbol SH2D1A
Gene ID (NCBI) 4068
RRIDAB_2239283
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO60880
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SH2D1A, also named as DSHP and SAP, is an inhibitor of the SLAM self-association. It acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. SH2D1A mediates interaction between FYN and SLAMF1. Defects in SH2D1A are a cause of lymphoproliferative syndrome X-linked type 1 (XLP1).