验证数据展示
经过测试的应用
Positive IHC detected in | human skin cancer tissue, human cervical cancer tissue, human placenta tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
应用 | 推荐稀释比 |
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Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
13639-1-AP targets DSS1 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, ELISA Application Description |
文献引用应用 | WB, IF, IHC |
经测试反应性 | human |
文献引用反应性 | human |
免疫原 | DSS1 fusion protein Ag4573 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | split hand/foot malformation (ectrodactyly) type 1 |
别名 | DSS1, ECD, SEM1, SHFD1, Shfdg1, SHFM1, SHSF1 |
计算分子量 | 70 aa, 8 kDa |
GenBank蛋白编号 | BC032782 |
基因名称 | DSS1 |
Gene ID (NCBI) | 7979 |
RRID | AB_2254633 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P60896 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
实验方案
Product Specific Protocols | |
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IHC protocol for DSS1 antibody 13639-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
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Nature BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.
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EMBO J The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response. | ||
J Med Genet Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I. | ||
Lab Invest Increased chemosensitivity via BRCA2-independent DNA damage in DSS1- and PCID2-depleted breast carcinomas.
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BMC Cancer Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival. | ||
Protein Cell DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells. |