验证数据展示
经过测试的应用
| Positive WB detected in | human peripheral blood platelets |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
14152-1-AP targets SLA2 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | SLA2 fusion protein Ag5334 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | Src-like-adaptor 2 |
| 别名 | Src like adapter 2, SLAP-2, SLAP2, SLAP 2, MARS |
| 计算分子量 | 261 aa, 29 kDa |
| 观测分子量 | 28-30 kDa |
| GenBank蛋白编号 | BC042041 |
| 基因名称 | SLA2 |
| Gene ID (NCBI) | 84174 |
| RRID | AB_3669179 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H6Q3 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SLA2 is an adapter protein, which negatively regulates T-cell receptor (TCR) signaling. It Inhibits T-cell antigen-receptor-induced activation of nuclear factor of activated T-cells and may act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL-dependent degradation of signaling proteins (PMID: 11696592).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SLA2 antibody 14152-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |