验证数据展示
产品信息
21932-1-PBS targets SLC14A2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | SLC14A2 fusion protein Ag16561 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | solute carrier family 14 (urea transporter), member 2 |
别名 | |
计算分子量 | 920 aa, 101 kDa |
观测分子量 | 43 kDa, 101 kDa |
GenBank蛋白编号 | BC110445 |
基因名称 | SLC14A2 |
Gene ID (NCBI) | 8170 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q15849 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC14A2, also known as human urea transporter -2 (HUT2), is the human homolog of UT-A2 and the only kidney-specific urea transporter cloned in humans. Urea transport in the kidney is mediated by a family of transporter proteins, including renal urea transporters (UT-A) and erythrocyte urea transporters (UT-B). UT-A proteins expressed in the kidney play a critical role in generating the hypertonic medulla, which is an integral component of the urinary concentrating mechanism (PMID: 11590132, 11880324). The 4.2-kb hUT-A1 cDNA encodes a 920-amino acid peptide, which is 89% identical to the rat UT-A1 protein (PMID: 11502588).