• Featured Product
  • KD/KO验证

URAT1 Polyclonal antibody

URAT1 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 14937-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat, pig

应用

WB, IHC, ELISA and More (1)

SLC22A12, RST, Renal-specific transporter, Renal specific transporter, Organic anion transporter 4-like protein

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse heart tissue, pig kidney tissue, mouse kidney tissue, rat heart tissue, rat kidney tissue
Positive IHC detected inmouse kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:6000
Immunohistochemistry (IHC)IHC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

14937-1-AP targets URAT1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human, mouse, rat, pig
文献引用反应性human, mouse, rat
免疫原 URAT1 fusion protein Ag6770 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 22 (organic anion/urate transporter), member 12
别名 SLC22A12, RST, Renal-specific transporter, Renal specific transporter, Organic anion transporter 4-like protein
计算分子量 60 kDa
观测分子量 65-70 kDa, 40 kDa
GenBank蛋白编号BC053348
基因名称 URAT1
Gene ID (NCBI) 116085
RRIDAB_2191270
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96S37
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Human urate anion exchanger (URAT1), also known as SLC22A12, is a urate transporter located in the proximal tubules of human kidney and responsible for urate reabsorption. Defects in gene encoding URAT1 cause hypouricemia renal type 1 (RHUC1). This antibody recognizes the native and glycosylated URAT1 between 65 and 70 kDa as well as the truncated 40kDa protein.

实验方案

Product Specific Protocols
WB protocol for URAT1 antibody 14937-1-APDownload protocol
IHC protocol for URAT1 antibody 14937-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Phytomedicine

Amelioration effects of α-viniferin on hyperuricemia and hyperuricemia-induced kidney injury in mice

Authors - Xiao-Li Guo
mouseWB

Mol Metab

URAT1-selective inhibition ameliorates insulin resistance by attenuating diet-induced hepatic steatosis and brown adipose tissue whitening in mice.

Authors - Yoshiro Tanaka
mouseIHC

Food Funct

Anti-hyperuricemic potential of stevia (Stevia rebaudiana Bertoni) residue extract in hyperuricemic mice

Authors - Arshad Mehmood
mouseWB

Int J Mol Sci

Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis.

Authors - Yiming Wang
ratWB

Food Funct

Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota

Authors - Nanhai Zhang
mouseWB

Nutrients

Chinese Sumac (Rhus chinensis Mill.) Fruits Prevent Hyperuricemia and Uric Acid Nephropathy in Mice Fed a High-Purine Yeast Diet

Authors - Nan Ma
Loading...