OAT3/SLC22A8 Polyclonal antibody

OAT3/SLC22A8 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 16844-1-AP

Print datasheet

Synonyms

SLC22A8, Organic anion/dicarboxylate exchanger, OAT3, hOAT3



经过测试的应用

Positive WB detected inmouse kidney tissue, mouse liver tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

16844-1-AP targets OAT3/SLC22A8 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity human, mouse
Cited Reactivityrat
Immunogen OAT3/SLC22A8 fusion protein Ag9795 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier family 22 (organic anion transporter), member 8
Synonyms SLC22A8, Organic anion/dicarboxylate exchanger, OAT3, hOAT3
Calculated Molecular Weight 542 aa, 60 kDa
Observed Molecular Weight60 kDa
GenBank Accession Numberbc022387
Gene Symbol SLC22A8
Gene ID (NCBI) 9376
RRIDAB_3663018
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8TCC7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

OAT3 (encoded by SLC22A8) is widely distributed in the kidney, liver, choroid plexus, olfactory mucosa, brain, retina, and placenta, but it is pre-dominantly expressed on the basolateral membrane of renal tubular cells. OAT3 plays a crucial role in the uptake, distribution, and excretion of various endogenous/exogenous substances. 16844-1-AP detected ~70 kDa is greater than predicted for Oat3 protein containing 542 amino acid (calculated Mr 59 kDa) and probably represents the glycosylated form (PMID:23389457).

实验方案

Product Specific Protocols
WB protocol for OAT3/SLC22A8 antibody 16844-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
ratWB

Naunyn Schmiedebergs Arch Pharmacol

Molecular mechanism of geniposide against ANIT-induced intrahepatic cholestasis by integrative analysis of transcriptomics and metabolomics

Authors - Junyi Zhang