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  • Featured Product
  • KD/KO Validated

SLC25A46 Polyclonal antibody

SLC25A46 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA and More (1)

Conjugate

Unconjugated

Cat no : 12277-1-AP

Print datasheet

Synonyms

SLC25A46, TB1

验证数据展示

  • WB analysis using 12277-1-AP

    WB analysis using 12277-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 12277-1-AP (SLC25A46 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

  • WB analysis of Jurkat using 12277-1-AP

    WB analysis of Jurkat using 12277-1-AP

    WB result of SLC25A46 antibody (12277-1-AP; 1:1500; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC25A46 transfected Jurkat cells.

  • IHC staining of human stomach using 12277-1-AP

    IHC staining of human stomach using 12277-1-AP

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 12277-1-AP (SLC25A46 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

经过测试的应用

Positive WB detected inJurkat cells, mouse brain tissue, rat brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12277-1-AP targets SLC25A46 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB, IF
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, rat
Immunogen SLC25A46 fusion protein Ag2923 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier family 25, member 46
Synonyms SLC25A46, TB1
Calculated Molecular Weight 418 aa, 46 kDa
Observed Molecular Weight 46 kDa
GenBank Accession NumberBC017169
Gene Symbol SLC25A46
Gene ID (NCBI) 91137
RRIDAB_2239384
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96AG3
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SLC25A46 belongs to the SLC25 family of mitochondrial carrier proteins.

实验方案

Product Specific Protocols
WB protocol for SLC25A46 antibody 12277-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Cell Metab

A High-Density Human Mitochondrial Proximity Interaction Network.

Authors - Hana Antonicka
View Article
WB

Sci Adv

Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1.

Authors - Odetta Antico
View Article
humanWB,IF

Brain

Loss of function of SLC25A46 causes lethal congenital pontocerebellar hypoplasia.

Authors - Jijun Wan
View Article
humanWB

EMBO Mol Med

SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.

Authors - Alexandre Janer
  • KD Validated
View Article
humanWB

J Pers Med

Reanalysis of Exome Data Identifies Novel SLC25A46 Variants Associated with Leigh Syndrome.

Authors - Qifei Li
View Article
humanWB

Mol Biol Cell

Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2 mediated hyperfusion of mitochondria.

Authors - Janos Steffen
  • KO Validated
View Article