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  • Featured Product
  • KD/KO Validated

SLC38A1 Polyclonal antibody, PBS Only

SLC38A1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28632-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 28632-1-AP (same clone as 28632-1-PBS)

    WB analysis using 28632-1-AP (same clone as 28632-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28632-1-AP (SLC38A1 antibody) at dilution of 1:7000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 28632-1-AP (same clone as 28632-1-PBS)

    WB analysis of HeLa using 28632-1-AP (same clone as 28632-1-PBS)

    WB result of SLC38A1 antibody (28632-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC38A1 transfected Jurkat cells. This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

    IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28632-1-AP (SLC38A1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

    IHC staining of mouse brain using 28632-1-AP (same clone as 28632-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28632-1-AP (SLC38A1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28632-1-PBS in a different storage buffer formulation.

产品信息

28632-1-PBS targets SLC38A1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen SLC38A1 fusion protein Ag30088 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier family 38, member 1
Synonyms
Calculated Molecular Weight 487 aa, 54 kDa
Observed Molecular Weight54 kDa, 60-70 kDa
GenBank Accession NumberBC010620
Gene Symbol SLC38A1
Gene ID (NCBI) 81539
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9H2H9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC38A1 (Sodium-coupled neutral amino acid transporter 1), is also named as SNAT1, which is a symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PMID:20599747, PMID:10891391). Inhibition of SLC38A1 reduced tumor growth, cellular migration, invasion, and induced senescence in melanoma cells (PMID:35565278). SLC38A1 was identified as a positive regulator of mTORC1 in neurons, which promoted ischemic brain damage by mTOR-autophagy system (PMID:31552299). SLC38A1 is mainly expressed in brain and placenta.