SLC39A5 Polyclonal antibody
SLC39A5 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | mouse kidney tissue, mouse liver tissue, mouse pancreas tissue, rat kidney tissue, rat liver tissue, rat pancreas tissue |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
WB | See 1 publications below |
产品信息
The immunogen of 17285-1-AP is SLC39A5 Fusion Protein expressed in E. coli.
Tested Applications | WB, ELISA Application Description |
Cited Applications | WB |
Tested Reactivity | human, mouse, rat |
Immunogen | SLC39A5 fusion protein Ag11067 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | solute carrier family 39 (metal ion transporter), member 5 |
Synonyms | LZT Hs7, SLC39A5, Zinc transporter ZIP5, ZIP 5, ZIP5, Zrt and Irt like protein 5 |
Calculated Molecular Weight | 539 aa, 56 kDa |
Observed Molecular Weight | 70 kDa |
GenBank Accession Number | BC027884 |
Gene Symbol | SLC39A5 |
Gene ID (NCBI) | 283375 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q6ZMH5 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SLC39A5 (Zip5) belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Most of ZIP members have eight predicted transmembrane domains and similar predicted topologies with the N- and C-termini of the protein located on the extracytoplasmic face of the membrane. Zip5 is a zinc uptake transporter that is specific for Zn(II) over other potential metal ion substrates. ZIP5 gene is most actively expressed in tissues involved in zinc homeostasis (intestine, visceral endoderm, pancreas) but is not induced during zinc deficiency. ZIP5 is localized to the basolateral surface of these cells under zinc-replete conditions but is internalized during periods of dietary zinc deficiency. These observations suggest that Zip5 plays a central role in controlling organismal zinc status. This antibody was generated against the N-terminal region of human SLC39A5 and is predicted to detect the endogenous level of SLC39A5 protein. The calculated molecular weight of SLC39A5 is 56 kDa. With glycosylation modification, the molecular weight of SLC39A5 will be migrated to 70 kDa.
实验方案
Product Specific Protocols | |
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WB protocol for SLC39A5 antibody 17285-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Animals (Basel) Analysis of the Association of Two SNPs in the Promoter Regions of the PPP2R5C and SLC39A5 Genes with Litter Size in Yunshang Black Goats |