验证数据展示
经过测试的应用
| Positive WB detected in | HepG2 cells, RAW 264.7 cells, mouse brain tissue, mouse kidney tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
17876-1-AP targets SLC6A18 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 | SLC6A18 fusion protein Ag11685 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | solute carrier family 6, member 18 |
| 别名 | SLC6A18, Xtrp2 |
| 计算分子量 | 628 aa, 71 kDa |
| 观测分子量 | ~70 kDa |
| GenBank蛋白编号 | BC056757 |
| 基因名称 | SLC6A18 |
| Gene ID (NCBI) | 348932 |
| RRID | AB_3085543 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96N87 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SLC6A18, also known as XTRP2 and B0AT3, belongs to the SLC6 family of proteins. SLC6A18 acts as specific transporters for neurotransmitters, amino acids and osmolytes such as betaine, taurine and creatine. SLC6A18 is highly expressed at the luminal membrane of kidney proximal tubules and displays 50% identity with SLC6A19 (B0AT1), which is the main neutral amino acid transporter in both kidney and small intestine (PMID: 19478081, PMID: 21420947).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SLC6A18 antibody 17876-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |