验证数据展示
产品信息
20216-1-AP targets SLIT1-Specific in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | slit homolog 1 (Drosophila) |
| 别名 | KIAA0813, MEGF4, SLIL1, Slit 1, slit homolog 1 (Drosophila), Slit homolog 1 protein, SLIT1, SLIT3 |
| 计算分子量 | 168 kDa |
| GenBank蛋白编号 | NM_003061 |
| 基因名称 | SLIT1 |
| Gene ID (NCBI) | 6585 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O75093 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SLIT1, also named as KIAA0813, MEGF4 and SLIL1, is thought to be act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development it is involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. This antibody is specific to SLIT1. It has no cross-reaction to SLIT2 and SLIT3. The antibody can’t recognize the isoform B (91kd) of SLIT1.