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SMC2 Recombinant antibody, PBS Only

SMC2 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241536E1

Cat no : 84835-2-PBS

Print datasheet

Synonyms

SMC protein 2, SMC 2, hCAP E, CAPE, CAP E

验证数据展示

  • WB analysis using 84835-2-RR (same clone as 84835-2-PBS)

    WB analysis using 84835-2-RR (same clone as 84835-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84835-2-RR (SMC2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84835-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84835-2-RR

    Affinity and Kinetic Characterization of 84835-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84835-2-RR against Human SMC2 were performed. The affinity constant is below 1 pM.

Planning an IHC experiment? We recommend our IHCeasy SMC2 Ready-To-Use IHC Kit. SMC2 primary antibody included.

产品信息

84835-2-PBS targets SMC2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen SMC2 fusion protein Ag33471 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name structural maintenance of chromosomes 2
Synonyms SMC protein 2, SMC 2, hCAP E, CAPE, CAP E
Calculated Molecular Weight136 kDa
Observed Molecular Weight 135-140 kDa
GenBank Accession NumberNM_001042550.1
Gene Symbol SMC2
Gene ID (NCBI) 10592
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO95347
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (PMID: 11136719).