验证数据展示
产品信息
67808-1-PBS targets SMCR7L in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse , rat samples.
Tested Applications | WB, IHC, IF-P, Indirect ELISA Application Description |
Tested Reactivity | Human, mouse , rat |
Immunogen | SMCR7L fusion protein Ag13775 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | Smith-Magenis syndrome chromosome region, candidate 7-like |
Synonyms | dJ1104E15.3, FLJ20232, HSU79252, MID51, MIEF1, SMCR7L |
Calculated Molecular Weight | 463 aa, 51 kDa |
Observed Molecular Weight | 48-51 kDa |
GenBank Accession Number | BC002587 |
Gene Symbol | SMCR7L |
Gene ID (NCBI) | 54471 |
RRID | AB_2918571 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9NQG6 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa (also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.