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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67808-1-Ig (same clone as 67808-1-PBS)

    WB analysis using 67808-1-Ig (same clone as 67808-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67808-1-Ig (SMCR7L/MID51 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 67808-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse testis using 67808-1-Ig (same clone as 67808-1-PBS)

    IHC staining of mouse testis using 67808-1-Ig (same clone as 67808-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 67808-1-Ig (SMCR7L/MID51 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67808-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse testis using 67808-1-Ig (same clone as 67808-1-PBS)

    IF Staining of mouse testis using 67808-1-Ig (same clone as 67808-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse testis tissue using SMCR7L/MID51 antibody (67808-1-Ig, Clone: 3B3G3 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67808-1-PBS in a different storage buffer formulation.

SMCR7L Monoclonal antibody, PBS Only

SMCR7L Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 67808-1-PBS

产品说明书

CloneNo. 3B3G3

宿主/亚型

Mouse / IgG2b

种属反应性

Human, mouse , rat

应用

WB, IHC, IF-P, Indirect ELISA

别名

dJ1104E15.3, FLJ20232, HSU79252, MID51, MIEF1, SMCR7L

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67808-1-PBS targets SMCR7L in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse , rat samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 Human, mouse , rat
免疫原 SMCR7L fusion protein Ag13775 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 Smith-Magenis syndrome chromosome region, candidate 7-like
别名 dJ1104E15.3, FLJ20232, HSU79252, MID51, MIEF1, SMCR7L
计算分子量 463 aa, 51 kDa
观测分子量48-51 kDa
GenBank蛋白编号BC002587
基因名称 SMCR7L
Gene ID (NCBI) 54471
RRIDAB_2918571
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9NQG6
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa (also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.