SMUG1 Polyclonal antibody

SMUG1 Polyclonal Antibody for WB, ELISA
Cat No. 19857-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

FDG, HMUDG, SMUG1, UNG3

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size: 

-/ -


经过测试的应用

Positive WB detected inCOLO 320 cells, HEK-293 cells, HeLa cells, K-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

19857-1-AP targets SMUG1 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen SMUG1 fusion protein Ag13934 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name single-strand-selective monofunctional uracil-DNA glycosylase 1
Synonyms FDG, HMUDG, SMUG1, UNG3
Calculated Molecular Weight 177 aa, 20 kDa
Observed Molecular Weight34 kDa
GenBank Accession NumberBC000417
Gene Symbol SMUG1
Gene ID (NCBI) 23583
RRIDAB_3085589
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ53HV7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

UNG(Uracil-DNA glycosylase) removes uracil in DNA resulting from deamination of cytosine or replicative incorporation of dUMP instead of dTMP. Thus, UNG plays a role in suppressing GC-to-AT transition mutations.The UNG gene encodes 2 isoforms that are individually targeted to the mitochondria and the nucleus(PMID:12369930).Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5). This antibody is specific to UNG.

实验方案

Product Specific Protocols
WB protocol for SMUG1 antibody 19857-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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