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SMYD4 Monoclonal antibody, PBS Only

SMYD4 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2F4B7

Cat no : 66874-1-PBS

Print datasheet

Synonyms

KIAA1936, SMYD4, ZMYND21

验证数据展示

  • WB analysis of MCF-7 using 66874-1-Ig (same clone as 66874-1-PBS)

    WB analysis of MCF-7 using 66874-1-Ig (same clone as 66874-1-PBS)

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 66874-1-Ig (SMYD4 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66874-1-PBS in a different storage buffer formulation.

产品信息

66874-1-PBS targets SMYD4 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen SMYD4 fusion protein Ag11552 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name SET and MYND domain containing 4
Synonyms KIAA1936, SMYD4, ZMYND21
Calculated Molecular Weight 804 aa, 89 kDa
Observed Molecular Weight 85-89 kDa
GenBank Accession NumberBC035077
Gene Symbol SMYD4
Gene ID (NCBI) 114826
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ8IYR2
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SMYD4, also named as SET and MYND domain-containing protein 4, is a 804 amino acid protein, which contains 1 MYND-type zinc finger and 1 SET domain. SMYD4 belongs to the class V-like SAM-binding methyltransferase superfamily. SMYD4, as a potential tumor suppressor, plays a critical role in breast carcinogenesis at least partly through inhibiting the expression of Pdgfr-alpha, and could be a novel target for improving treatment of breast cancer. SMYD4 is a muscle-specific transcriptional modulator involved in development.