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SNX18 Recombinant antibody, PBS Only (Capture)

SNX18 Uni-rAbTM Recombinant Antibody for IF/ICC, Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241537A2

Cat no : 84215-1-PBS

Print datasheet

Synonyms

Sorting nexin-18, SH3PXD3B, SH3 and PX domain-containing protein 3B, 241537A2

验证数据展示

  • IF Staining of MCF-7 using 84215-1-RR (same clone as 84215-1-PBS)

    IF Staining of MCF-7 using 84215-1-RR (same clone as 84215-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using SNX18 antibody (84215-1-RR, Clone: 241537A2 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84215-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01150-1

    Cytometric bead array standard curve of MP01150-1

    Cytometric bead array standard curve of MP01150-1, SNX18 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84215-1-PBS. Detection antibody: 84215-3-PBS. Standard: Ag16645. Range: 0.313-40 ng/mL.

产品信息

84215-1-PBS targets SNX18 as part of a matched antibody pair:

MP01150-1: 84215-1-PBS capture and 84215-3-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications IF/ICC, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen SNX18 fusion protein Ag16645 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name sorting nexin 18
Synonyms Sorting nexin-18, SH3PXD3B, SH3 and PX domain-containing protein 3B, 241537A2
Calculated Molecular Weight 628 aa, 69 kDa
GenBank Accession NumberBC060791
Gene Symbol SNX18
Gene ID (NCBI) 112574
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ96RF0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SNXs (sorting nexins) are a diverse group of cytoplasmic and membrane-associated proteins that are classified by the presence of a phospholipid-binding motif-the PX domain (PMID:12461558). SNXs are involved in endocytosis and protein trafficking. SNX18, together with SNX9 and SNX33, constitutes a separate SNX9 subfamily which is required for mitosis through endocytosis processes (PMID: 22718350, 20427313). SNX18 acts as a positive regulator of autophagy and regulates ATG9A trafficking from recycling endosomes (PMID: 24113029, 29437695).