SORD Monoclonal antibody

SORD Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, rat, mouse and More (1)

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

4A8E1

Cat no : 67625-1-Ig

Print datasheet

Synonyms

L iditol 2 dehydrogenase, SDH, sorbitol dehydrogenase, SORD, SORD1



经过测试的应用

Positive WB detected inLNCaP cells, HSC-T6 cells, PC-12 cells, NIH/3T3 cells, Hela cells, HepG2 cells, Jurkat cells, K-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

67625-1-Ig targets SORD in WB, ELISA applications and shows reactivity with Human, rat, mouse samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity Human, rat, mouse
Cited Reactivityhuman, mouse
Immunogen SORD fusion protein Ag8651 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name sorbitol dehydrogenase
Synonyms L iditol 2 dehydrogenase, SDH, sorbitol dehydrogenase, SORD, SORD1
Calculated Molecular Weight 357 aa, 38 kDa
Observed Molecular Weight 38 kDa
GenBank Accession NumberBC021085
Gene Symbol SORD
Gene ID (NCBI) 6652
RRIDAB_2882826
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ00796
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SORD(Sorbitol dehydrogenase) is also named as L-iditol 2-dehydrogenase and belongs to the zinc-containing alcohol dehydrogenase family. It catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. This protein can form a homotetramer(PMID:12962626). Measurement of SORD is a specific indicator of liver cell damage and parenchymal.

实验方案

Product Specific Protocols
WB protocol for SORD antibody 67625-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

J Nutr

Sucrose intake elevates erythritol in plasma and urine in male mice

Authors - Semira R Ortiz
  • KO Validated
humanWB

Front Nutr

Erythritol synthesis is elevated in response to oxidative stress and regulated by the non-oxidative pentose phosphate pathway in A549 cells

Authors - Semira R. Ortiz
  • KD Validated