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验证数据展示

  • WB analysis using 22213-1-AP

    WB analysis using 22213-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 22213-1-AP (SOSTDC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • IF Staining of Saos-2 using 22213-1-AP

    IF Staining of Saos-2 using 22213-1-AP

    Immunofluorescent analysis of (-20°C Methanol) fixed Saos-2 cells using SOSTDC1 antibody (22213-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L).

SOSTDC1 Polyclonal antibody

SOSTDC1 Polyclonal Antibody for WB, IF/ICC, ELISA
Cat No. 22213-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, ELISA

别名

CDA019, Ectodermal BMP inhibitor, ECTODIN, sclerostin domain containing 1, SOSTDC1, USAG 1, USAG1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inhuman milk
Positive IF/ICC detected inSaos-2 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

22213-1-AP targets SOSTDC1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human
免疫原 SOSTDC1 fusion protein Ag17538 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sclerostin domain containing 1
别名 CDA019, Ectodermal BMP inhibitor, ECTODIN, sclerostin domain containing 1, SOSTDC1, USAG 1, USAG1
计算分子量 206 aa, 23 kDa
观测分子量 23-26 kDa
GenBank蛋白编号BC008484
基因名称 SOSTDC1
Gene ID (NCBI) 25928
RRIDAB_3085688
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ6X4U4
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SOSTDC1 (Sclerostin domain-containing protein 1), also known as Ectodin (Ectodermal BMP inhibitor), is a member of the sclerostin family. It is an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain and is highly abundant in milk and kidney. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.

实验方案

Product Specific Protocols
WB protocol for SOSTDC1 antibody 22213-1-APDownload protocol
IF protocol for SOSTDC1 antibody 22213-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols