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SOX17 Polyclonal antibody

SOX17 Polyclonal Antibody for WB, ELISA
Cat No. 24903-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA and More (1)

Transcription factor SOX-17, Transcription factor SOX 17

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inC6 cells, PC-3 cells, mouse embryo

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24903-1-AP targets SOX17 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB, IF
经测试反应性 human, mouse, rat
文献引用反应性human, mouse, rat
免疫原 SOX17 fusion protein Ag19157 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 SRY (sex determining region Y)-box 17
别名 Transcription factor SOX-17, Transcription factor SOX 17
计算分子量 414 aa, 44 kDa
观测分子量 44 kDa
GenBank蛋白编号BC111365
基因名称 SOX17
Gene ID (NCBI) 64321
RRIDAB_2879789
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H6I2
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Transcription factor SOX 17 (SOX17) also named as SRY box 17 is a 414 amino acid protein, which contains one Sox C-terminal domain and one HMG box DNA-binding domain. SOX17 as a transcription regulator binds target promoter DNA and bend the DNA via WNT3A. SOX17 is a marker of endodermal cells and a transcriptional regulator containing a DNA binding domain called the HMG box. In mouse embryos, SOX17 plays critical roles in the growth and differentiation of definitive endodermal cells (PMID: 11973269), the remodeling of endothelial cells (PMID: 16895970), hindgut endoderm expansion with localization of primordial germ cells (PMID: 19371732), and gallbladder/bile duct formation (PMID: 19913509).

实验方案

Product Specific Protocols
WB protocol for SOX17 antibody 24903-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIF

Mater Today Bio

Nanofiber-microwell cell culture system for spatially patterned differentiation of pluripotent stem cells in 3D

Authors - Youyi Tai
mouseWB

Stem Cell Reports

Phosphorylation of Threonine343 Is Crucial for OCT4 Interaction with SOX2 in the Maintenance of Mouse Embryonic Stem Cell Pluripotency.

Authors - Xianmixinuer Abulaiti
mouseWB

Front Cell Dev Biol

ADNP Controls Gene Expression Through Local Chromatin Architecture by Association With BRG1 and CHD4.

Authors - XiaoYun Sun
humanIF

Stem Cell Res

Establishment of an arrhythmogenic right ventricular cardiomyopathy derived iPSC cell line (USFi004-A) carrying a heterozygous mutation in PKP2 (c.1799delA).

Authors - Jiajia Yang
humanIF

Stem Cell Res

Generation of a Friedreich's Ataxia patient-derived iPSC line USFi001-A.

Authors - Mariana Burgos Angulo
humanIF

Stem Cell Res

Generation of an iPSC cell line (USFi003-A) from a patient with dilated cardiomyopathy carrying a heterozygous mutation in LMNA (p.R541C).

Authors - Jiajia Yang
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