SSTR2 Polyclonal antibody

SSTR2 Polyclonal Antibody for IHC, IF/ICC, ELISA
Cat No. 20404-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF/ICC, ELISA and More (1)

SS2 R, SS 2 R, SRIF-1, SRIF 1, Somatostatin receptor type 2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive IHC detected inmouse pancreas tissue, human pancreas tissue, human kidney tissue, mouse stomach tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inNeuro-2a cells

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:200-1:800
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

20404-1-AP targets SSTR2 in IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF/ICC, ELISA Application Description
文献引用应用IHC, IF
经测试反应性 human, mouse
文献引用反应性human, mouse
免疫原 SSTR2 fusion protein Ag14205 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 somatostatin receptor 2
别名 SS2 R, SS 2 R, SRIF-1, SRIF 1, Somatostatin receptor type 2
计算分子量 369 aa, 41 kDa
GenBank蛋白编号BC019610
基因名称 SSTR2
Gene ID (NCBI) 6752
RRIDAB_2878683
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP30874
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Somatostatin receptor 2 (SSTR2) is a G-protein coupled membrane receptor expressed in a variety of neural and neurosecretory tissue types. In neuroendocrine tumors (NETs), in which Somatostatin receptors (SSTRs) are commonly expressed, the detection of SSTR2 expression has both diagnostic and therapeutic potential. Besides NETs, SSTR2 immunostaining can be detected in other types of tumor cells(PMID:34786053). Moreover, SSTR2 is consistently expressed in Olfactory neuroblastoma (ONB) suggesting a role for somatostatin-analog based imaging and therapy in this disease. More generally, SSTR2 may be another marker of neuroendocrine diferentiation in ONB(PMID:33929681). SSTR2 has 2 isoforms with the MW of 40-41 kDa.

实验方案

Product Specific Protocols
IHC protocol for SSTR2 antibody 20404-1-APDownload protocol
IF protocol for SSTR2 antibody 20404-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Appl Radiat Isot

Autoradiography on deparaffinized tissue sections - A feasibility study with 68Ga-labeled PET-tracers

Authors - Eva-Maria Klebermass
mouseIF

Acta Neuropathol Commun

Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer's disease

Authors - Jaemyung Jang
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