SSTR5 Monoclonal antibody

SSTR5 Monoclonal Antibody for WB, IF-P, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat and More (3)

Applications

WB, IF-P, ELISA and More (2)

Conjugate

Unconjugated

CloneNo.

2B10D8

Cat no : 66772-1-Ig

Print datasheet

Synonyms

somatostatin receptor 5, Somatostatin receptor type 5, SS 5 R, SS5 R, SS5R, SST5, SSTR5



经过测试的应用

Positive WB detected inHSC-T6 cells, HeLa cells, HEK-293 cells, HepG2 cells, NIH/3T3 cells, Neuro-2a cells
Positive IF-P detected inmouse kidney tissue
Planning an IF experiment? We recommend our CoraLite® Plus 488 and CoraLite®594 conjugated versions of this antibody.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunofluorescence (IF)-PIF-P : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

66772-1-Ig targets SSTR5 in WB, IF-P, CoIP, ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Applications WB, IF-P, ELISA Application Description
Cited ApplicationsWB, IF, CoIP
Tested Reactivity Human, Mouse, Rat
Cited Reactivityhuman, mouse, rat
Immunogen SSTR5 fusion protein Ag18615 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name somatostatin receptor 5
Synonyms somatostatin receptor 5, Somatostatin receptor type 5, SS 5 R, SS5 R, SS5R, SST5, SSTR5
Calculated Molecular Weight 364 aa, 39 kDa
Observed Molecular Weight 41 kDa
GenBank Accession NumberBC146576
Gene Symbol SSTR5
Gene ID (NCBI) 6755
RRIDAB_2882118
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP35346
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Somatostatin is a widely distributed peptide with a broad range of biological actions. Two biological forms of somatostatin exist: somatostatin-14 and -28. Somatostatin receptors (SSTR1, 2A and B, 3, 4 and 5) belong to the G protein coupled receptor family and have a wide expression pattern in both normal tissues and solid tumors (PMID: 23872332). SSTR5 has greater affinity for somatostatin-28 than somatostatin-14 (PMID: 8373420).

实验方案

Product Specific Protocols
WB protocol for SSTR5 antibody 66772-1-IgDownload protocol
IF protocol for SSTR5 antibody 66772-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
ratWB

Phytomedicine

Differential effect of polysaccharide and nonpolysaccharide components in Sijunzi decoction on spleen deficiency syndrome and their mechanisms.

Authors - Ping Ma
mouseWB

Endocr J

Differential effects of β-arrestin1 and β-arrestin2 on somatostatin receptors in murine AtT-20 corticotroph tumor cells.

Authors - Kazunori Kageyama
humanIF

Front Endocrinol (Lausanne)

Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5 homo- and hetero-dimer formation

Authors - Donatella Treppiedi
humanWB,CoIP

Cell Death Discov

Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models

Authors - Yumeng Wang