ST2/IL-1RL1 Recombinant antibody

ST2/IL-1RL1 Uni-rAbTM Recombinant Antibody for ELISA
Cat No. 83459-1-RR
CloneNo. 240142G3

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

ELISA

IL1RL1, IL-1RL1, FIT 1, EC:3.2.2.6, DER4

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy IL1RL1/ST2 Ready-To-Use IHC Kit. IL1RL1/ST2 primary antibody included.

产品信息

83459-1-RR targets ST2/IL-1RL1 in ELISA applications and shows reactivity with Human samples.

Tested Applications ELISA Application Description
Tested Reactivity Human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name interleukin 1 receptor-like 1
Synonyms IL1RL1, IL-1RL1, FIT 1, EC:3.2.2.6, DER4
Calculated Molecular Weight 63 kDa, 37 kDa, 30 kDa
GenBank Accession NumberBC030975
Gene Symbol IL1RL1
Gene ID (NCBI) 9173
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ01638-2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ST2, also known as IL-1RL1, is a member of the IL-1 superfamily and serves as the receptor for IL-33. It plays a major role in immune and inflammatory responses. ST2 is expressed by various types of immune cells including Th2 cells, mast cells, type 2 innate lymphoid cells, eosinophils, basophils, NK cells, and non-immune cells, including cardiomyocytes. Two forms of ST2 exist: a membrane-bound form and a soluble form (sST2). The membrane-bound form activates the MyD88/NF-κB signaling pathway to enhance mast cell, Th2, regulatory T cell (Treg), and innate lymphoid cell type 2 functions. sST2 acts as a decoy receptor. (PMID: 27055914; 23999434; 28484466)

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