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ST3GAL6 Polyclonal antibody

ST3GAL6 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 13154-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, ELISA and More (1)

Sialyltransferase 10, SIAT10, ST3Gal VI, ST3GAL6, ST3GALVI

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inMCF-7 cells, human heart tissue, Sp2/0 cells, human placenta tissue
Positive IHC detected inhuman liver tissue, human urothelial carcinoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:8000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13154-1-AP targets ST3GAL6 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human, mouse
文献引用反应性human, mouse
免疫原 ST3GAL6 fusion protein Ag3782 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
别名 Sialyltransferase 10, SIAT10, ST3Gal VI, ST3GAL6, ST3GALVI
计算分子量 331 aa, 38 kDa
观测分子量 50-60 kDa
GenBank蛋白编号BC023312
基因名称 ST3GAL6
Gene ID (NCBI) 10402
RRIDAB_10646441
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y274
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ST3GAL6, also named as SIAT10, belongs to the glycosyltransferase 29 family. ST3GAL6 is involved in the synthesis of sialyl-paragloboside, which is a precursor of sialyl-Lewis X determinant. ST3GAL6 has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. ST3GAL6 is known to promote cell adhesion and migration of multiple myeloma cells by increasing the synthesis of selectin ligands. ST3GAL6 has 2 isoforms with the molecular mass of 25 and 38 kDa. Sometimes higher molecular weight about 50-60 kDa can also be observed, which may be a glycosylated modified variant of ST3GAL6. (PMID: 31914669, 30220088)

实验方案

Product Specific Protocols
WB protocol for ST3GAL6 antibody 13154-1-APDownload protocol
IHC protocol for ST3GAL6 antibody 13154-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Int J Oncol

lncRNA ST3GAL6‑AS1 promotes invasion by inhibiting hnRNPA2B1‑mediated ST3GAL6 expression in multiple myeloma.

Authors - Ying Shen
  • KD Validated
humanWB,IHC

FEBS Lett

The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo.

Authors - Ming Yu
human,mouseWB

J Zhejiang Univ Sci B

Sialyltransferase ST3GAL6 silencing reduces α2,3-sialylated glycans to regulate autophagy by decreasing HSPB8-BAG3 in the brain with hepatic encephalopathy

Authors - Xiaocheng Li
humanWB

J Zhejiang Univ Sci B

Sialyltransferase ST3GAL6 silencing reduces α2,3-sialylated glycans to regulate autophagy by decreasing HSPB8-BAG3 in the brain with hepatic encephalopathy

Authors - Xiaocheng Li
humanIF

Antiviral Res

Preventing human influenza and coronaviral mono or coinfection by blocking virus-induced sialylation

Authors - Md Ruhul Amin
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