验证数据展示
经过测试的应用
| Positive WB detected in | L02 cells, MCF-7 cells, T-47D cells |
| Positive IP detected in | mouse testis tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
17567-1-AP targets ST7L in WB, IHC, IP, CoIP, ELISA applications and shows reactivity with mouse, human samples.
| 经测试应用 | WB, IP, ELISA Application Description |
| 文献引用应用 | WB, IHC, CoIP |
| 经测试反应性 | mouse, human |
| 文献引用反应性 | human |
| 免疫原 | ST7L fusion protein Ag11768 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | suppression of tumorigenicity 7 like |
| 别名 | FAM4B, ST7 related protein, ST7L, ST7R, STLR |
| 计算分子量 | 575 aa, 65 kDa |
| 观测分子量 | 60-70 kDa |
| GenBank蛋白编号 | BC065501 |
| 基因名称 | ST7L |
| Gene ID (NCBI) | 54879 |
| RRID | AB_2194882 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8TDW4 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ST7 (suppressor of tumorigenicity 7) gene has been proposed to be a tumor suppressor gene, product of which is a multi-pass membrane protein belonging to the ST7 family. ST7L (suppressor of tumorigenicity 7 protein-like) gene encodes a multi-pass membrane protein also belonging to the ST7 family, 8 isoforms produced by alternative splicing have been described . However, the molecular function of this gene product has not been determined so far.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for ST7L antibody 17567-1-AP | Download protocol |
| IP protocol for ST7L antibody 17567-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Cell Death Dis MicroRNA-23b functions as an oncogene and activates AKT/GSK3β/β-catenin signaling by targeting ST7L in hepatocellular carcinoma. | ||
J Exp Clin Cancer Res Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression. | ||
Int J Mol Med miR-378 functions as an onco-miRNA by targeting the ST7L/Wnt/β-catenin pathway in cervical cancer. | ||
Life Sci Landscape of multiple tissues' gene expression pattern associated with severe sepsis: Genetic insights from Mendelian randomization and trans-omics analysis |
