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STMN3 Polyclonal antibody

STMN3 Polyclonal Antibody for WB, ELISA
Cat No. 11311-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA and More (2)

SCG10 like protein, SCLIP, Stathmin 3, stathmin like 3, STMN3

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inSH-SY5Y cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:20000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11311-1-AP targets STMN3 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原 STMN3 fusion protein Ag1853 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 stathmin-like 3
别名 SCG10 like protein, SCLIP, Stathmin 3, stathmin like 3, STMN3
计算分子量 21 kDa
观测分子量 21-25 kDa
GenBank蛋白编号BC009381
基因名称 STMN3
Gene ID (NCBI) 50861
RRIDAB_2197399
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NZ72
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Stathmin family phosphoproteins participate in the control of microtubule dynamics and have been proposed to be involved in the control of neuronal differentiation. Neuron specific Stathmin-3 (STMN3) is a novel STAT3 (signal transducer and activator of transcription 3) interacting protein. STAT3 is a key contributor to cancer cell migration and invasion. STMN3 exhibits microtubule-destabilizing activity, which is antagonized by STAT3. SCG10 is a widely studied and recognized neuronal differentiation marker, STMN3 is a SCG10-like protein (SCLIP) and is present from the earliest stages of hippocampal neuron differentiation in culture at vesicle-like structures following dynamic microtubules. RNAi mediated inhibition of this gene resulted in increased axonal branching.

实验方案

Product Specific Protocols
WB protocol for STMN3 antibody 11311-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB, IHC

Cancer Res

Coordinated expression of stathmin family members by far upstream sequence element-binding protein-1 increases motility in non-small cell lung cancer.

Authors - Stephan Singer
humanWB

Cancer Res

RUNX1 is a driver of renal cell carcinoma correlating with clinical outcome.

Authors - Nicholas Rooney
mouseWB,IF

Elife

HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.

Authors - Alicia Tapias
humanWB

Mol Cancer Ther

PMID: 23543364

Authors - Xie Xuemei X
  • KD Validated
mouseWB

J Biol Chem

The Stathmin-2 membrane targeting domain is required for axon protection and regulated degradation by DLK signaling

Authors - Emma J C Thornburg-Suresh
WB

BMC Cell Biol

CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited.

Authors - Matthew A Helsby
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