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STMN3 Monoclonal antibody, PBS Only

STMN3 Monoclonal Antibody for WB,Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB,Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F12B1

Cat No : 66152-1-PBS

Print datasheet

Synonyms

SCG10 like protein, SCLIP, Stathmin 3, stathmin like 3, STMN3

验证数据展示

  • WB analysis of human brain using 66152-1-Ig (same clone as 66152-1-PBS)

    WB analysis of human brain using 66152-1-Ig (same clone as 66152-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 66152-1-Ig (STMN3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66152-1-PBS in a different storage buffer formulation.

产品信息

66152-1-PBS targets STMN3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB,Indirect ELISA Application Description
Tested Reactivity human
Immunogen STMN3 fusion protein Ag18844 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name stathmin-like 3
Synonyms SCG10 like protein, SCLIP, Stathmin 3, stathmin like 3, STMN3
Calculated Molecular Weight 21 kDa
Observed Molecular Weight 21 kDa
GenBank Accession NumberBC009381
Gene Symbol STMN3
Gene ID (NCBI) 50861
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NZ72
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Stathmin family phosphoproteins participate in the control of microtubule dynamics and have been proposed to be involved in the control of neuronal differentiation. Neuron specific Stathmin-3 (STMN3) is a novel STAT3 (signal transducer and activator of transcription 3) interacting protein. STAT3 is a key contributor to cancer cell migration and invasion. STMN3 exhibits microtubule-destabilizing activity, which is antagonized by STAT3. SCG10 is a widely studied and recognized neuronal differentiation marker, STMN3 is a SCG10-like protein (SCLIP) and is present from the earliest stages of hippocampal neuron differentiation in culture at vesicle-like structures following dynamic microtubules. RNAi mediated inhibition of this gene resulted in increased axonal branching.