• Featured Product
  • KD/KO验证

Syntaxin 2 Polyclonal antibody

Syntaxin 2 Polyclonal Antibody for WB, IF/ICC, ELISA
Cat No. 55033-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse and More (1)

应用

WB, IF/ICC, ELISA and More (2)

EPIM, Epimorphin, EPM, STX2, STX2A, STX2B, STX2C, syntaxin 2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inA431 cells, HeLa cells
Positive IF/ICC detected inHeLa cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

55033-1-AP targets Syntaxin 2 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, ELISA Application Description
文献引用应用WB, IF, IHC
经测试反应性 human, mouse
文献引用反应性human, rat
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 syntaxin 2
别名 EPIM, Epimorphin, EPM, STX2, STX2A, STX2B, STX2C, syntaxin 2
计算分子量 33 kDa
观测分子量 32 kDa
GenBank蛋白编号NM_001980
基因名称 Syntaxin 2
Gene ID (NCBI) 2054
RRIDAB_11182166
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP32856
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

Syntaxin 2 (STX2), also named as EPIM, STX2A, STX2B and STX2C, belongs to the syntaxin family. It is essential for epithelial morphogenesis. STX2 is a member of the SNARE membrane fusion machinery which localized to the midbody during cytokinesis in rat and canine kidney cell lines. Inhibition of STX2 and Vamp8 function by overexpression of nonmembrane-anchored mutants caused failure of cytokinesis leading to the formation of binucleated cells. Time-lapse microscopy showed that only midbody abscission and not further upstream events, such as furrowing, were affected. The antibody is specific to STX2.

实验方案

Product Specific Protocols
WB protocol for Syntaxin 2 antibody 55033-1-APDownload protocol
IF protocol for Syntaxin 2 antibody 55033-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IHC,IF

Cell Death Dis

STX2 promotes colorectal cancer metastasis through a positive feedback loop that activates the NF-κB pathway.

Authors - Yongxia Wang
  • KD Validated
humanWB

J Cell Sci

Syntaxin 7 contributes to breast cancer cell invasion by promoting invadopodia formation.

Authors - Sameena Parveen
humanWB,IHC

Life Sci

STX2 drives colorectal cancer proliferation via upregulation of EXOSC4.

Authors - Yong-Xia Wang
  • KD Validated
humanIHC, WB

J Cancer

Syntaxin 2 promotes colorectal cancer growth by increasing the secretion of exosomes.

Authors - Yongxia Wang
ratWB

Neuroscience

SNAP25/syntaxin4/VAMP2/Munc18-1 Complexes in Spinal Dorsal Horn Contributed to Inflammatory Pain.

Authors - Xing-Lian Duan
Loading...