SU5214

SU5214 (SU 5214) 是 VEGFR2 抑制剂,IC50值为 14.8 µM(FLK-1) 和 36.7 µM (EGFR)。摘自专利文献 US5834504A 中的化合物 SU5214。

CAS号

186611-04-1

分子式

C16H13NO2

主要靶点

Tyrosinase|VEGFR

仅限科研使用

Cat No : CM05610

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Synonyms

SU 5214



产品信息

SU 5214 is a modulator of tyrosine kinase signal transduction.

CAS号 186611-04-1
分子式 C16H13NO2
主要靶点 Tyrosinase|VEGFR
主要通路 蛋白酪氨酸激酶|血管生成|蛋白酶体
分子量 251.29
纯度 99.55%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 SU 5214

靶点活性

Flk-1:14.8 μM (IC50)

溶解度

DMSO:2.51 mg/mL (10 mM)

参考文献

1.Silva JC,et al.Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions. Sci Rep. 2016 Oct 18;6:35284.
2.Dorobisz T,et al. Incidental gallbladder cancer after cholecystectomy: 1990 to 2014. Onco Targets Ther. 2016 Aug 8;9:4913-6.

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