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验证数据展示

  • IHC staining of human colon cancer using 14240-1-AP (same clone as 14240-1-PBS)

    IHC staining of human colon cancer using 14240-1-AP (same clone as 14240-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 14240-1-AP (SUCLG2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14240-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 14240-1-AP (same clone as 14240-1-PBS)

    IHC staining of human colon cancer using 14240-1-AP (same clone as 14240-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 14240-1-AP (SUCLG2 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14240-1-PBS in a different storage buffer formulation.

  • WB analysis using 14240-1-AP (same clone as 14240-1-PBS)

    WB analysis using 14240-1-AP (same clone as 14240-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14240-1-AP (SUCLG2 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14240-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse kidney using 14240-1-AP (same clone as 14240-1-PBS)

    IP experiment of mouse kidney using 14240-1-AP (same clone as 14240-1-PBS)

    IP result of anti-SUCLG2 (IP:14240-1-AP, 4ug; Detection:14240-1-AP 1:600) with mouse kidney tissue lysate 4800ug. This data was developed using the same antibody clone with 14240-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

SUCLG2 Polyclonal antibody, PBS Only

SUCLG2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 14240-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

14240-1-PBS targets SUCLG2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 SUCLG2 fusion protein Ag5495 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 succinate-CoA ligase, GDP-forming, beta subunit
别名
计算分子量 47 kDa
观测分子量 47 kDa
GenBank蛋白编号BC047024
基因名称 SUCLG2
Gene ID (NCBI) 8801
RRIDAB_2197187
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96I99
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SUCLG2, encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. The deficiency of SUCLG2 represents an encephalomyopathic form of mtDNA depletion syndromes (PMID:30470562). Mutated SUCLG1 causes mislocalization of SUCLG2 protein, morphological alterations of mitochondria and an early-onset severe neurometabolic disorder. SUCLG2 is mainly expressed in liver, kidney, heart (PMID: 9765291).