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  • Featured Product
  • KD/KO Validated

SUCLG2 Polyclonal antibody, PBS Only

SUCLG2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 14240-1-PBS

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Synonyms

验证数据展示

  • IHC staining of human colon cancer using 14240-1-AP (same clone as 14240-1-PBS)

    IHC staining of human colon cancer using 14240-1-AP (same clone as 14240-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 14240-1-AP (SUCLG2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14240-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 14240-1-AP (same clone as 14240-1-PBS)

    IHC staining of human colon cancer using 14240-1-AP (same clone as 14240-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 14240-1-AP (SUCLG2 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14240-1-PBS in a different storage buffer formulation.

  • WB analysis using 14240-1-AP (same clone as 14240-1-PBS)

    WB analysis using 14240-1-AP (same clone as 14240-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14240-1-AP (SUCLG2 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14240-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse kidney using 14240-1-AP (same clone as 14240-1-PBS)

    IP experiment of mouse kidney using 14240-1-AP (same clone as 14240-1-PBS)

    IP result of anti-SUCLG2 (IP:14240-1-AP, 4ug; Detection:14240-1-AP 1:600) with mouse kidney tissue lysate 4800ug. This data was developed using the same antibody clone with 14240-1-PBS in a different storage buffer formulation.

产品信息

14240-1-PBS targets SUCLG2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SUCLG2 fusion protein Ag5495 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name succinate-CoA ligase, GDP-forming, beta subunit
Synonyms
Calculated Molecular Weight 47 kDa
Observed Molecular Weight 47 kDa
GenBank Accession NumberBC047024
Gene Symbol SUCLG2
Gene ID (NCBI) 8801
RRIDAB_2197187
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96I99
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SUCLG2, encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. The deficiency of SUCLG2 represents an encephalomyopathic form of mtDNA depletion syndromes (PMID:30470562). Mutated SUCLG1 causes mislocalization of SUCLG2 protein, morphological alterations of mitochondria and an early-onset severe neurometabolic disorder. SUCLG2 is mainly expressed in liver, kidney, heart (PMID: 9765291).