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Sapropterin dihydrochloride

Sapropterin dihydrochloride (6R-BH4 dihydrochloride) 是一种合成的 BH4 形式，已经被批准用于 BH4 反应的 PKU 研究。

CAS号

69056-38-8

分子式

C9H17Cl2N5O3

主要靶点

Hydroxylase

仅限科研使用

Cat No : CM04678

Print datasheet

Synonyms

6R-BH4 dihydrochloride|Sapropterin Hydrochloride|6R-Tetrahydro-L-biopterin dihydrochloride|(6R)-5,6,7,8-四氢生物蝶呤 二盐酸盐|盐酸沙丙蝶呤

验证数据展示

  • CAS No.: 69056-38-8

    Sapropterin dihydrochloride
    CAS#: 69056-38-8

产品信息

Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.

CAS号 69056-38-8
分子式 C9H17Cl2N5O3
主要靶点 Hydroxylase
主要通路 代谢
分子量 314.17
纯度 99.46%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 6R-BH4 dihydrochloride|Sapropterin Hydrochloride|6R-Tetrahydro-L-biopterin dihydrochloride|(6R)-5,6,7,8-四氢生物蝶呤 二盐酸盐|盐酸沙丙蝶呤

溶解度

H2O:260 mg/mL (827.58 mM),Sonification is recommended.

参考文献

1.Vanoxerine, a New Drug for Terminating Atrial Fibrillation and Flutter[J]. J Cardiovasc Electrophysiol, 2010, 21(3):311-319.
2.Winn S R , Scherer T , Beat Thöny, et al. High dose sapropterin dihydrochloride therapy improves monoamine neurotransmitter turnover in murine phenylketonuria (PKU)[J]. Molecular Genetics and Metabolism, 2015, 117(1):5-11.

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